Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134434 | 0.91 | ALDH1A1 (0.49) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL7318438 | 0.88 | ALDH1A1 (0.53) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL6135040 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6135046 | 0.83 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPTITGB3 | |
| SCHEMBL63474 | 0.83 | ALDH1A1 (0.59) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL6135234 | 0.81 | ALDH1A1 (0.55) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL6135228 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL63892 | 0.81 | ALDH1A1 (0.63) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL6134915 | 0.80 | ALDH1A1 (0.65) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6135117 | 0.80 | HRH3 (0.42) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | ALDH1A1 3841/4885POLB 1754/4885MEN1 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.