Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7317609 | 0.84 | TP53 (0.41) | SIRT2RARARARBRARGCA12 | |
| Trifluoroacetic Acid SCHEMBL7325659 | 0.84 | SIRT2 (0.46) | SIRT2RARARARBRARGCA12 | |
| Trifluoroacetic Acid SCHEMBL7324043 | 0.84 | MTOR (0.42) | SIRT2RARARARBRARGCA12 | |
| Trifluoroacetic Acid SCHEMBL7323148 | 0.84 | LMNA (0.48) | SIRT2CA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL6134998 | 0.83 | SIRT2 (0.40) | SIRT2CA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL7320929 | 0.81 | ALDH1A1 (0.42) | SIRT2DPP4DPP7CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6132409 | 0.81 | MAPT (0.41) | SIRT2DPP4DPP7CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6132355 | 0.80 | MAPT (0.38) | RARARARBRARGDPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL6134395 | 0.80 | MAPT (0.42) | SIRT2DPP4DPP7MAPTTP53 | |
| Trifluoroacetic Acid SCHEMBL7316392 | 0.80 | TP53 (0.47) | RARARARBRARGCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261177-A1 | Compound | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261177-A1 | Compound | MANBA, MAN2B1, MAN2A1 | SIRT2 3486/4885RARA 4826/4885RARB 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.