Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585912 | 0.89 | TSHR (0.36) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL18585910 | 0.89 | TSHR (0.36) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL5808330 | 0.79 | POLB (0.61) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL18585915 | 0.79 | SLC6A1 (0.50) | TSHRKMT2ASMN1; SMN2ALOX15NOS2 | |
| SCHEMBL490371 | 0.79 | SLC6A1 (0.50) | TSHRKMT2ASMN1; SMN2ALOX15NOS2 | |
| SCHEMBL5808630 | 0.75 | POLB (0.52) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL3224577 | 0.74 | POLB (0.50) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL6957802 | 0.73 | TSHR (0.52) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL18938813 | 0.73 | POLB (0.54) | POLBTSHRGABRPGABRDGABRA1 | |
| SCHEMBL4588348 | 0.73 | POLB (0.54) | POLBTSHRGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591462-A2 | Temperature-responsive polymer compound and process for producing the same | Amersham Biosciences KK (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-6956077-B1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK (JP) | 2005-10-18 | — | — | US | disclosed |
| US-20050224415-A1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK | 2005-10-13 | — | — | US | disclosed |
| EP-1153049-B1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | AMERSHAM BIOSCIENCES KK (JP) | 2005-08-10 | — | — | EP | disclosed |
| EP-1153049-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | Amersham Pharmacia Biotech K.K. (JP) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000044800-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-08-03 | — | — | WO | disclosed |