Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.50 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585915 | 1.00 | SLC6A1 (0.50) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL18585910 | 0.90 | TSHR (0.36) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL18585912 | 0.90 | TSHR (0.36) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL6135434 | 0.79 | POLB (0.46) | TSHRSMN1; SMN2KMT2ACYP2D6NOS2 | |
| SCHEMBL6994878 | 0.79 | SLC6A1 (0.62) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL21397458 | 0.78 | ULK1 (0.53) | LMNATNKSTNKS2ULK1ROCK2 | |
| SCHEMBL4629910 | 0.77 | SLC6A1 (0.55) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL23936828 | 0.77 | SLC6A1 (0.59) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL6950605 | 0.77 | SLC6A1 (0.59) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL18284919 | 0.75 | SLC6A1 (0.41) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834520-B2 | Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-12-05 | — | — | US | claimed |
| US-20230055665-A1 | DELIVERY CARRIER INTO CELL | ITO, KABUSIKIKAISYA (JP) | 2023-02-23 | — | — | US | claimed |
| US-20220213146-A1 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. | 2022-07-07 | — | — | US | claimed |
| US-20220169688-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-06-02 | — | — | US | claimed |
| EP-3962933-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | Dana-Farber Cancer Institute, Inc. (US) | 2022-03-09 | — | — | EP | claimed |
| EP-3737404-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | Dana Farber Cancer Institute, Inc. (US) | 2020-11-18 | — | — | EP | claimed |
| WO-2020215005-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-22 | — | — | WO | claimed |
| WO-2019118719-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-06-20 | — | — | WO | claimed |
| US-20190002514-A1 | PEPTIDES BINDING TO BFL-1 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-03 | — | — | US | claimed |
| US-20190002506-A1 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-03 | — | — | US | claimed |
| EP-3341008-A2 | PEPTIDES BINDING TO BFL-1 | Dana-Farber Cancer Institute, Inc. (US) | 2018-07-04 | — | — | EP | claimed |
| WO-2017040323-A2 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-09 | — | — | WO | claimed |
| WO-2017040329-A2 | PEPTIDES BINDING TO BFL-1 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-09 | — | — | WO | claimed |
| US-8486722-B1 | Sensing method for biopolymers and sensing device therefor | NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) | 2013-07-16 | — | — | US | claimed |
| US-20130164862-A1 | SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR | TANAKA SABURO (JP) | 2013-06-27 | — | — | US | claimed |
| US-8105493-B2 | Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit | JNC CORPORATION (JP) | 2012-01-31 | — | — | US | claimed |
| US-20090001025-A1 | AGGREGATION AND DISPERSION METHODS OF MAGNETIC PARTICLES, SEPARATION AND DETECTION METHODS USING THE SAME AND DETECTION KIT | CHISSO CORPORATION (JP) | 2009-01-01 | — | — | US | claimed |
| EP-2009442-A2 | Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit | Chisso Corporation (JP) | 2008-12-31 | — | — | EP | claimed |
| US-20070218567-A1 | SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR | NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) | 2007-09-20 | — | — | US | claimed |
| US-20240228539-A9 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-11 | — | — | US | disclosed |
| US-20240132544-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | DANA FARBER CANCER INST INC (US) | 2024-04-25 | — | — | US | disclosed |
| US-11834520-B2 | Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230055665-A1 | DELIVERY CARRIER INTO CELL | ITO, KABUSIKIKAISYA (JP) | 2023-02-23 | — | — | US | disclosed |
| US-20220213146-A1 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. | 2022-07-07 | — | — | US | disclosed |
| US-20220169688-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-06-02 | — | — | US | disclosed |
| EP-3962933-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | Dana-Farber Cancer Institute, Inc. (US) | 2022-03-09 | — | — | EP | disclosed |
| US-11078246-B2 | Peptides binding to Bfl-1 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20210070802-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | DANA-FARBER CANCER INSTITUTE, INC. | 2021-03-11 | — | — | US | disclosed |
| EP-3765852-A1 | STABILIZED PEPTIDES FOR BIOMARKER DETECTION | Dana Farber Cancer Institute, Inc. (US) | 2021-01-20 | — | — | EP | disclosed |
| US-20200408746-A1 | Stabilized Peptides for Biomarker Detection | DANA-FARBER CANCER INSTITUTE, INC. | 2020-12-31 | — | — | US | disclosed |
| EP-3737404-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | Dana Farber Cancer Institute, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| WO-2020215005-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-22 | — | — | WO | disclosed |
| WO-2020027234-A1 | ANALYSIS METHOD, REAGENT KIT, AND ANALYZING DEVICE | キヤノンメディカルシステムズ株式会社 | 2020-02-06 | — | — | WO | disclosed |
| WO-2019178313-A1 | STABILIZED PEPTIDES FOR BIOMARKER DETECTION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019118719-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| US-20190170758-A1 | METHOD OF DETECTION WITH A FLUORESCENT LABELING PARTICLE | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-10203326-B2 | Method of detecting target substance | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20190011442-A1 | METHOD FOR DETECTING SUBSTANCE OF INTEREST, METHOD FOR QUANTIFYING SUBSTANCE OF INTEREST, KIT, AND METHOD FOR PREPARING REAGENT | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| US-20190002506-A1 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-03 | — | — | US | disclosed |
| US-20190002514-A1 | PEPTIDES BINDING TO BFL-1 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-01-03 | — | — | US | disclosed |
| US-20180348228-A1 | Method of Determining Quantity of Objects to be Detected in Specimen | ORTHO CLINICAL DIAGNOSTICS KK (JP) | 2018-12-06 | — | — | US | disclosed |
| EP-3054283-B1 | METHOD FOR DETECTING TARGET SUBSTANCE | FURUKAWA ELECTRIC CO LTD (JP) | 2018-12-05 | — | — | EP | disclosed |
| EP-3341008-A2 | PEPTIDES BINDING TO BFL-1 | Dana-Farber Cancer Institute, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017040329-A2 | PEPTIDES BINDING TO BFL-1 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017040323-A2 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20160291003-A1 | METHOD OF DETECTING TARGET SUBSTANCE | FURUKAWA ELECTRIC CO., LTD. (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3054297-A1 | FLUORESCENCE-LABELED PARTICLE | Furukawa Electric Co. Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| EP-3054283-A1 | METHOD FOR DETECTING TARGET SUBSTANCE | Furukawa Electric Co. Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-20160216273-A1 | FLUORESCENT LABELING PARTICLE | FURUKAWA ELECTRIC CO., LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| EP-2711747-A1 | INFRARED SHIELDING FILM, METHOD FOR PRODUCING INFRARED SHIELDING FILM, AND INFRARED SHIELD | Konica Minolta, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-8486722-B1 | Sensing method for biopolymers and sensing device therefor | NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) | 2013-07-16 | — | — | US | disclosed |
| US-20130164862-A1 | SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR | TANAKA SABURO (JP) | 2013-06-27 | — | — | US | disclosed |
| US-8372659-B2 | Sensing method for biopolymers and sensing device therefor | NATIONAL UNIVERSITY CORPORATION TOYOHASHI UNIVERSITY OF TECHNOLOGY (JP) | 2013-02-12 | — | — | US | disclosed |
| US-8105503-B2 | Method of storing thermoresponsive polymer in state of aqueous solution | CHISSO CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-8105493-B2 | Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit | JNC CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110233453-A1 | METHOD OF STORING THERMORESPONSIVE POLYMER IN STATE OF AQUEOUS SOLUTION | CHISSO CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-7976728-B2 | Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same | JNC CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20110155947-A1 | LYOPHILIZABLE TEMPERATURE-RESPONSIVE MAGNETIC FINE PARTICLES | CHISSO CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| EP-2009044-B1 | Method of storing an aqueous dispersion of particle modified with a polymer having upper critical solution temperature | JNC CORP (JP) | 2011-06-15 | — | — | EP | disclosed |
| EP-2320437-A1 | TEMPERATURE-RESPONSIVE MAGNETIC FINE GRAINS CAPABLE OF FREEZE DRYING | Chisso Corporation (JP) | 2011-05-11 | — | — | EP | disclosed |
| US-20090001321-A1 | AQUEOUS SOLUTION OF POLYMER HAVING UPPER CRITICAL SOLUTION TEMPERATURE, AQUEOUS DISPERSION OF PARTICLE MODIFIED WITH THE POLYMER AND METHOD OF STORING THE SAME | CHISSO CORPORATION (JP) | 2009-01-01 | — | — | US | disclosed |
| US-20090001025-A1 | AGGREGATION AND DISPERSION METHODS OF MAGNETIC PARTICLES, SEPARATION AND DETECTION METHODS USING THE SAME AND DETECTION KIT | CHISSO CORPORATION (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009044-A1 | Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same | Chisso Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2009442-A2 | Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit | Chisso Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20070218567-A1 | SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR | NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070218567-A1 | SENSING METHOD FOR BIOPOLYMERS AND SENSING DEVICE THEREFOR | NATIONAL UNIV CORP TOYOHASHI UNIV OF TECHNOLOGY (JP) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834520-B2 | Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides | MCL1, BCL2L1, BCL2L11 | SLC6A1 4841/4885SLC6A11 4860/4885TSHR 3201/4885 |
| US-11078246-B2 | Peptides binding to Bfl-1 | BCL2L11, BCL2L1, BCL2L13 | SLC6A1 4222/4885SLC6A11 4317/4885TSHR 3904/4885 |
| US-20190002514-A1 | PEPTIDES BINDING TO BFL-1 | BCL2L11, BCL2L1, BCL2L13 | SLC6A1 4222/4885SLC6A11 4317/4885TSHR 3904/4885 |
| US-20240132544-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | MCL1, BCL2L1, BCL2L11 | SLC6A1 4841/4885SLC6A11 4860/4885TSHR 3201/4885 |
| US-20190002506-A1 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | HSPBP1, HSPA8, PTMS | SLC6A1 4798/4885SLC6A11 4805/4885TSHR 2652/4885 |
| US-20230055665-A1 | DELIVERY CARRIER INTO CELL | CTSA, ATG4A, ATG7 | SLC6A1 1672/4885SLC6A11 2112/4885TSHR 4448/4885 |
| US-20220169688-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | UBE2E1, MDM2, UBA1 | SLC6A1 4711/4885SLC6A11 4797/4885TSHR 3845/4885 |
| US-20210070802-A1 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | MCL1, BCL2L1, BCL2L11 | SLC6A1 4841/4885SLC6A11 4860/4885TSHR 3201/4885 |
| US-20220213146-A1 | STABILIZED PEPTIDES FOR COVALENT BINDING TO TARGET PROTEIN | HSPBP1, HSPA8, PTMS | SLC6A1 4798/4885SLC6A11 4805/4885TSHR 2652/4885 |
| US-20240228539-A9 | SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES | MCL1, BCL2L1, BCL2L11 | SLC6A1 4841/4885SLC6A11 4860/4885TSHR 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.