Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL1833539 | 0.95 | KMT2A (0.55) | KMT2AKDM4EMAPTLMNATSHR | |
| SCHEMBL9397484 | 0.91 | KMT2A (0.47) | KMT2AKDM4EMAPTLMNATSHR | |
| Tyrosine SCHEMBL5605978 | 0.88 | KMT2A (0.60) | KMT2AKDM4EMAPTLMNATSHR | |
| SCHEMBL9225869 | 0.85 | KDM4E (0.52) | KMT2AKDM4EMAPTLMNATSHR | |
| SCHEMBL7356307 | 0.85 | KDM4E (0.63) | KMT2AKDM4EMAPTLMNATSHR | |
| Tyrosine SCHEMBL9449484 | 0.84 | KDM4E (0.63) | KMT2AKDM4EMAPTLMNATSHR | |
| SCHEMBL8366913 | 0.84 | KDM4E (0.51) | KMT2AKDM4EMAPTLMNATSHR | |
| Tyrosine SCHEMBL1065122 | 0.84 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL27895091 | 0.82 | KDM4E (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Phenylalanine SCHEMBL9668359 | 0.81 | MEN1 (0.39) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594819-A1 | IRREVERSIBLE CASPASE-3 INHIBITORS AS ACTIVE SITE PROBES | Merck Frosst Canada & Co. (CA) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069773-A1 | IRREVERSIBLE CASPASE-3 INHIBITORS AS ACTIVE SITE PROBES | MERCK FROSST CANADA LTD. (CA) | 2004-08-19 | — | — | WO | disclosed |