Tyrosine

Tyrosine

SCHEMBL9449484

C[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.63
MAPT P10636 3/20 0.63
KMT2A Q03164 3/20 0.63
LMNA P02545 2/20 0.63
TSHR P16473 2/20 0.63
BLM P54132 2/20 0.63
PMP22 Q01453 2/20 0.63
MEN1 O00255 2/20 0.63
MPO P05164 1/20 0.63
HIF1A Q16665 1/20 0.63
TACR1 P25103 2/20 0.56
HTR1A P08908 2/20 0.54
HTR2A P28223 2/20 0.54
HTR2C P28335 2/20 0.54
SLC6A4 P31645 2/20 0.54
HTR7 P34969 2/20 0.54
HTR2B P41595 2/20 0.54
ALDH1A1 P00352 1/20 0.54
CYP3A4 P08684 1/20 0.54
ADORA3 P0DMS8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL1065122 0.94 KMT2A (0.68) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL9449482 0.91 KDM4E (0.73) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL9449493 0.91 KDM4E (0.73) KDM4EMAPTKMT2ALMNATSHR
SCHEMBL10359013 0.91 TACR1 (0.62) KDM4EMAPTKMT2ALMNATSHR
SCHEMBL243575 0.91 TACR1 (0.62) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL243574 0.89 KMT2A (0.80) KDM4EMAPTKMT2ALMNATSHR
D-Tryptophan SCHEMBL10359012 0.89 KMT2A (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL15168746 0.89 KMT2A (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL6032938 0.89 KMT2A (0.80) KDM4EMAPTKMT2ALMNATSHR
D-Tryptophan SCHEMBL10359011 0.89 KMT2A (0.80) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5185157-A With solid or liquid carrier, free of zinc, magnesium and calcium salts TYSON & ASSOCIATES, INC. 1993-02-09 US disclosed