Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 9/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 8/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL6135474 | 0.91 | KMT2A (0.50) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tyrosine SCHEMBL1833539 | 0.86 | KMT2A (0.55) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tyrosine SCHEMBL5605978 | 0.85 | KMT2A (0.60) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL6864436 | 0.83 | KMT2A (0.42) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL28205631 | 0.83 | KMT2A (0.65) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL7356307 | 0.82 | KDM4E (0.63) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tyrosine SCHEMBL9449484 | 0.81 | KDM4E (0.63) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tyrosine SCHEMBL1065122 | 0.81 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL15555538 | 0.81 | SLC7A5 (0.48) | ERAP2LNPEPSLC6A2 | |
| SCHEMBL6032937 | 0.81 | KMT2A (0.71) | KMT2AKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1436239-A | Novel enzyme gene and expression product thereof | OTSUKA PHARMA CO LTD (JP) | 2003-08-13 | — | — | CN | disclosed |
| WO-1994028018-A2 | SYNTHETIC STERICALLY-CONSTRAINED CATALYSTS | ATASSI ZOUHAIR (US) | 1994-12-08 | — | — | WO | disclosed |