SCHEMBL6135582 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	5/20	0.46

▸	MMP3	P08254	5/20	0.46

▸	MEN1	O00255	1/20	0.45

▸	KMT2A	Q03164	1/20	0.45

▸	PDF	Q9HBH1	2/20	0.44

▸	BMP1	P13497	1/20	0.43

▸	ALDH1A1	P00352	1/20	0.43

▸	SMN1; SMN2	Q16637	1/20	0.43

▸	LMNA	P02545	1/20	0.42

▸	TSHR	P16473	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7529199	0.95	MMP2 (0.49)	MMP2MMP3BMP1
SCHEMBL13333341	0.90	KMT2A (0.42)	MMP2MMP3KMT2APDFALDH1A1
SCHEMBL13333322	0.89	MMP2 (0.47)	MMP2MMP3MEN1KMT2APDF
SCHEMBL5497357	0.87	MMP2 (0.44)	MMP2MMP3PDFBMP1
SCHEMBL5497359	0.87	MMP2 (0.44)	MMP2MMP3PDFBMP1
SCHEMBL14282177	0.87	MEN1 (0.46)	MMP2MMP3MEN1KMT2APDF
SCHEMBL13333271	0.86	ALDH1A1 (0.48)	MEN1KMT2AALDH1A1SMN1; SMN2LMNA
SCHEMBL13333286	0.86	KMT2A (0.46)	MMP2MMP3MEN1KMT2APDF
SCHEMBL6135733	0.85	MMP2 (0.44)	MMP2MMP3PDFBMP1
SCHEMBL6758740	0.85	MAPT (0.42)	MMP2MMP3PDFBMP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1210330-B1	ANTIBACTERIAL AGENTS	VERNALIS OXFORD LTD (GB)	2005-04-20	—	—	EP	claimed