SCHEMBL6135733

SCHEMBL6135733

CCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N1CCC(O)(Cc2ccccc2)CC1)C(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.44
MMP3 P08254 7/20 0.44
PDF Q9HBH1 2/20 0.42
BMP1 P13497 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6135582 0.85 MMP2 (0.46) MMP2MMP3PDFBMP1
SCHEMBL14282177 0.85 MEN1 (0.46) MMP2MMP3PDFBMP1
SCHEMBL5497357 0.83 MMP2 (0.44) MMP2MMP3PDFBMP1
SCHEMBL5497359 0.83 MMP2 (0.44) MMP2MMP3PDFBMP1
SCHEMBL13333286 0.82 KMT2A (0.46) MMP2MMP3PDFBMP1
SCHEMBL13333273 0.82 CCR1 (0.50) MMP2MMP3PDFBMP1
SCHEMBL14066495 0.82 MMP2 (0.45) MMP2MMP3PDFBMP1
SCHEMBL7529199 0.81 MMP2 (0.49) MMP2MMP3BMP1
SCHEMBL14282179 0.81 PDF (0.54) MMP2MMP3PDF
SCHEMBL13333285 0.81 CCKBR (0.47) MMP2MMP3PDF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210330-B1 ANTIBACTERIAL AGENTS VERNALIS OXFORD LTD (GB) 2005-04-20 EP claimed