Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135674 | 1.00 | BMP1 (0.47) | BMP1BIRC2CTSLCTSSMME | |
| SCHEMBL7114508 | 0.89 | BIRC2 (0.52) | BMP1BIRC2MMEECE1MMP2 | |
| SCHEMBL7114506 | 0.89 | BIRC2 (0.52) | BMP1BIRC2MMEECE1MMP2 | |
| SCHEMBL6135650 | 0.84 | MEN1 (0.50) | BMP1BIRC2CTSLCTSSMME | |
| SCHEMBL7084246 | 0.84 | BIRC2 (0.53) | BMP1BIRC2MMP2MMP1MMP3 | |
| SCHEMBL7118008 | 0.84 | BIRC2 (0.53) | BMP1BIRC2MMP2MMP1MMP3 | |
| SCHEMBL7116705 | 0.83 | MMP2 (0.49) | BMP1MMP2MMP3 | |
| SCHEMBL7116708 | 0.83 | MMP2 (0.49) | BMP1MMP2MMP3 | |
| SCHEMBL14282135 | 0.81 | BMP1 (0.52) | BMP1BIRC2MMP2MMP1MMP3 | |
| SCHEMBL7118243 | 0.81 | BIRC2 (0.62) | BMP1BIRC2MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908911-B1 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2005-06-21 | — | — | US | claimed |
| EP-1210330-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-04-20 | — | — | EP | claimed |
| US-6908911-B1 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2005-06-21 | — | — | US | disclosed |
| EP-1210330-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-04-20 | — | — | EP | disclosed |