Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585197 | 0.76 | CALCRL (0.41) | — | |
| SCHEMBL6135719 | 0.73 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL4593853 | 0.69 | ROCK2 (0.43) | — | |
| SCHEMBL4585974 | 0.66 | CALCRL (0.44) | — | |
| SCHEMBL4587306 | 0.65 | CYP3A4 (0.41) | — | |
| SCHEMBL3561990 | 0.61 | GABRP (0.41) | — | |
| SCHEMBL29722741 | 0.61 | GABRP (0.41) | — | |
| SCHEMBL5391193 | 0.60 | KDM4E (0.34) | — | |
| SCHEMBL28771094 | 0.60 | CNR2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29061151 | 0.59 | CNR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539766-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2003104236-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-18 | — | — | WO | claimed |