Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753614 | 0.86 | ALDH1A1 (0.54) | RXFP1KDM4EALDH1A1SMN1; SMN2BRPF1 | |
| SCHEMBL7630835 | 0.82 | KDM4E (0.55) | RXFP1KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL10066976 | 0.80 | RXFP1 (0.64) | RXFP1KDM4EALDH1A1SMN1; SMN2BRPF1 | |
| SCHEMBL7956961 | 0.79 | ALDH1A1 (0.58) | KDM4EALDH1A1SMN1; SMN2HTR7GAA | |
| SCHEMBL6669660 | 0.78 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA | |
| SCHEMBL3453978 | 0.78 | ALDH1A1 (0.65) | KDM4EALDH1A1SMN1; SMN2HTR7RBP4 | |
| SCHEMBL15529774 | 0.78 | RXFP1 (0.90) | RXFP1 | |
| SCHEMBL8341399 | 0.77 | ALDH1A1 (0.56) | RXFP1KDM4EALDH1A1SMN1; SMN2HTR7 | |
| Hydrochloric Acid SCHEMBL15048947 | 0.77 | ALDH1A1 (0.63) | KDM4EALDH1A1SMN1; SMN2HTR7RBP4 | |
| SCHEMBL4212045 | 0.77 | LMNA (0.63) | KDM4EALDH1A1SMN1; SMN2HTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385495-A4 | SULFONAMIDES | SMITHKLINE BEECHAM CORP (US) | 2005-12-21 | — | — | EP | claimed |
| EP-1385495-A2 | SULFONAMIDES | SmithKline Beecham Corporation (US) | 2004-02-04 | — | — | EP | claimed |
| WO-2002089740-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | claimed |