Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 7/20 | 0.40 |
| ▸ | CHUK | O15111 | 4/20 | 0.40 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951887 | 0.75 | BCAT2 (0.53) | BCAT2DHODHIKBKBCHUKPKMYT1 | |
| SCHEMBL18816714 | 0.73 | DHODH (0.46) | BCAT2DHODHIKBKBBRD4CDC7 | |
| SCHEMBL3837776 | 0.73 | DHODH (0.46) | BCAT2DHODHIKBKBBRD4CDC7 | |
| SCHEMBL6838773 | 0.72 | ESR2 (0.44) | MAPT | |
| SCHEMBL20233004 | 0.72 | KAT6A (0.56) | BCAT2DHODHIKBKBCHUKPKMYT1 | |
| SCHEMBL6887769 | 0.72 | BCAT2 (0.56) | BCAT2DHODHIKBKBCHUKPKMYT1 | |
| SCHEMBL18816701 | 0.69 | BCAT2 (0.53) | BCAT2DHODHIKBKBCHUKPKMYT1 | |
| SCHEMBL5499374 | 0.69 | DHODH (0.45) | BCAT2DHODHIKBKBCHUKPKMYT1 | |
| SCHEMBL30009492 | 0.69 | BCAT2 (0.49) | BCAT2DHODHIKBKBCHUKPKMYT1 | |
| SCHEMBL27635536 | 0.69 | BCAT2 (0.56) | BCAT2IKBKBCHUKPKMYT1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107436-A1 | phenyl and pyridyl derivatives such as 3-Fluoro-N-(2'-trifluoromethyl-biphenyl-4-yl)-isonicotinamide, used as immunosuppressants for the treatmet or prevent inflammatory and immune disorders | SYNTA PHARMACEUTICALS CORP. | 2005-05-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107436-A1 | phenyl and pyridyl derivatives such as 3-Fluoro-N-(2'-trifluoromethyl-biphenyl-4-yl)-isonicotinamide, used as immunosuppressants for the treatmet or prevent inflammatory and immune disorders | TPMT, PTPN3, FKBP3 | BCAT2 835/4885DHODH 1620/4885IKBKB 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.