Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203595 | 0.77 | GAA (0.65) | GAASMN1; SMN2MEN1KMT2ACHRNA7 | |
| SCHEMBL4962589 | 0.77 | GAA (0.68) | GAASMN1; SMN2MEN1KMT2ACHRNB4 | |
| SCHEMBL3932594 | 0.76 | GAA (0.70) | GAASMN1; SMN2MEN1KMT2ACHRNA7 | |
| SCHEMBL5802421 | 0.74 | GAA (0.61) | GAASMN1; SMN2MEN1KMT2ACHRNA7 | |
| SCHEMBL7955416 | 0.74 | GAA (0.64) | GAAMEN1KMT2ATACR1 | |
| SCHEMBL5127058 | 0.74 | GAA (0.64) | GAASMN1; SMN2MEN1KMT2ACHRNA7 | |
| SCHEMBL8252682 | 0.71 | GAA (0.68) | GAASMN1; SMN2MEN1KMT2ACHRNA7 | |
| SCHEMBL3434676 | 0.68 | GAA (0.56) | GAASMN1; SMN2MEN1KMT2ACHRNB4 | |
| SCHEMBL6014519 | 0.68 | CHRNB4 (0.55) | GAACHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9371575 | 0.68 | CHRNB4 (0.55) | GAACHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341812-A | A kind of preparation method containing quinuclidine compounds | 科贝源(北京)生物医药科技有限公司 | 2018-07-31 | — | — | CN | disclosed |
| EP-1551833-A1 | PROCESS FOR THE PREPARATION OF (S,S)-CIS-2-BENZHYDRYL-3-BENZYLAMINOQUINUCLIDINE | Pfizer Products Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| US-20050085641-A1 | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine | PFIZER INC. | 2005-04-21 | — | — | US | disclosed |
| US-6861526-B2 | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine | PFIZER INC. (US) | 2005-03-01 | — | — | US | disclosed |
| US-20040116704-A1 | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine | PFIZER INC. | 2004-06-17 | — | — | US | disclosed |
| WO-2004035575-A1 | PROCESS FOR THE PREPARATION OF (S,S)-CIS-2-BENZHYDRYL-3-BENZYLAMINOQUINUCLIDINE | PFIZER PRODUCTS, INC. (US) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085641-A1 | Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine | BCKDK, SRM, SKP1 | GAA 2403/4885SMN1; SMN2 1601/4885MEN1 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.