SCHEMBL6136123

SCHEMBL6136123

CC(=O)OC(C(C)=O)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.52
SLC28A2 O43868 1/20 0.52
SLC29A1 Q99808 1/20 0.52
SLC28A3 Q9HAS3 1/20 0.52
P2RY2 P41231 10/20 0.47
P2RY4 P51582 4/20 0.47
P2RY14 Q15391 2/20 0.47
P2RY6 Q15077 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337862 0.90 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5847159 0.87 SLC28A1 (0.53) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL31186989 0.83 SLC28A1 (0.56) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5950218 0.82 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4653181 0.81 TK1 (0.45)
SCHEMBL6292694 0.80 DUT (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17825821 0.80 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL23710653 0.79 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL566228 0.79 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21275617 0.79 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1402071-A4 METHODS AND PRODUCTS FOR ANALYZING NUCLEIC ACIDS BASED ON METHYLATION STATUS US GENOMICS INC (US) 2005-12-14 EP disclosed
EP-1402071-A2 METHODS AND PRODUCTS FOR ANALYZING NUCLEIC ACIDS BASED ON METHYLATION STATUS U.S. Genomics, Inc. (US) 2004-03-31 EP disclosed
WO-2002101353-A2 METHODS AND PRODUCTS FOR ANALYZING NUCLEIC ACIDS BASED ON METHYLATION STATUS U.S. GENOMICS, INC. (US) 2002-12-19 WO disclosed