SCHEMBL566228

SCHEMBL566228

CC(O)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 10/20 0.53
P2RY6 Q15077 7/20 0.50
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
P2RY4 P51582 3/20 0.49
P2RY14 Q15391 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23710653 1.00 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL800228 1.00 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL800550 1.00 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL21275617 1.00 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16629728 1.00 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13174543 0.90 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13190779 0.90 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13190777 0.90 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5846581 0.89 SLC28A1 (0.63) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL800388 0.88 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4599889-A2 SIRNA AND THEIR USE IN METHODS AND COMPOSITIONS FOR INHIBITING THE EXPRESSION OF THE NRARP GENE Sylentis S.A.U. (ES) 2025-08-13 EP claimed
EP-3347470-B1 SIRNA AND THEIR USE IN METHODS AND COMPOSITIONS FOR INHIBITING THE EXPRESSION OF THE NRARP GENE SYLENTIS SAU (ES) 2025-07-09 EP claimed
WO-2025109162-A1 SIRNA AND COMPOSITIONS FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF OCULAR RETINAL CONDITIONS SYLENTIS S.A.U. (ES) 2025-05-30 WO claimed
WO-2025109166-A1 SIRNA AND COMPOSITIONS FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF OCULAR RETINAL CONDITIONS SYLENTIS S.A.U. (ES) 2025-05-30 WO claimed
EP-4560020-A1 SIRNA AND COMPOSITIONS FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF OCULAR RETINAL CONDITIONS Sylentis S.A.U. (ES) 2025-05-28 EP claimed
EP-4560019-A1 SIRNA AND COMPOSITIONS FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF OCULAR RETINAL CONDITIONS Sylentis S.A.U. (ES) 2025-05-28 EP claimed
US-20240254485-A1 SIRNAS TARGETING SLC10A1 TRANSCRIPTS, COMPOSITIONS AND USES THEREOF Hemoshear Therapeutics, Inc. 2024-08-01 US claimed
US-10752896-B2 siRNA and their use in methods and compositions for inhibiting the expression of the NRARP gene SYLENTIS SAU (ES) 2020-08-25 US claimed
US-20180340177-A1 SIRNA AND THEIR USE IN METHODS AND COMPOSITIONS FOR INHIBITING THE EXPRESSION OF THE NRARP GENE SYLENTIS SAU (ES) 2018-11-29 US claimed
US-20170251660-A1 NUCLEOSIDE-CONTAINING COMPOSITIONS AND METHODS FOR TREATING RED BLOOD CELLS VIACELL, LLC 2017-09-07 US claimed
US-20110229871-A1 NUCLEOSIDE-CONTAINING COMPOSITIONS AND METHODS FOR TREATING RED BLOOD CELLS VIACELL, LLC 2011-09-22 US claimed
WO-2011103177-A1 NUCLEOSIDE-CONTAINING COMPOSITIONS AND METHODS FOR TREATING RED BLOOD CELLS VIACELL, LLC (US) 2011-08-25 WO claimed
US-20050119214-A1 Nuclease resistant double-stranded ribonucleic acid ALNYLAM PHARMACEUTICALS, INC. 2005-06-02 US claimed
WO-2026098677-A1 DOUBLE-STRANDED RNA FOR REGULATING ALK7 EXPRESSION, CONJUGATE THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 苏州时安生物技术有限公司 2026-05-15 WO disclosed
US-12618068-B2 Replicase cycling reaction (RCR) and the related SamRNA designs thereof LIN SHI LUNG (US) 2026-05-05 US disclosed
US-20250354144-A1 TARGETING MUC1-C WITH A NOVEL ANTISENSE OLIGONUCLEOTIDE FOR THE TREATMENT OF CANCER DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-11-20 US disclosed
EP-0549686-A4 MODIFIED INTERNUCLEOSIDE LINKAGES GILEAD SCIENCES INC (US) 1995-01-18 EP disclosed
EP-0582157-A1 Method of purifying nucleoside derivatives Ajinomoto Co., Inc. (JP) 1994-02-09 EP disclosed
EP-0549686-A1 MODIFIED INTERNUCLEOSIDE LINKAGES GILEAD SCIENCES, INC. (US) 1993-07-07 EP disclosed
WO-1992005186-A1 MODIFIED INTERNUCLEOSIDE LINKAGES GILEAD SCIENCES (US) 1992-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050119214-A1 Nuclease resistant double-stranded ribonucleic acid RNASE1, RNASEH1, RNASEL SLC28A1 1775/4885SLC28A2 1601/4885SLC29A1 1237/4885
US-12618068-B2 Replicase cycling reaction (RCR) and the related SamRNA designs thereof RNGTT, SLIRP, RNMT SLC28A1 2695/4885SLC28A2 2582/4885SLC29A1 3026/4885
US-20240254485-A1 SIRNAS TARGETING SLC10A1 TRANSCRIPTS, COMPOSITIONS AND USES THEREOF SLC20A1, SLC10A1, SLC10A6 SLC28A1 10/4885SLC28A2 34/4885SLC29A1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.