Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 15/20 | 0.76 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.76 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456941 | 0.87 | GRIN2B (1.00) | GRIN2BGRIN1NOS2 | |
| SCHEMBL17196594 | 0.87 | GRIN2B (1.00) | GRIN2BGRIN1NOS2 | |
| SCHEMBL19688443 | 0.84 | GRIN2B (1.00) | GRIN2BGRIN1NOS2 | |
| SCHEMBL27750271 | 0.80 | GRIN2B (0.61) | GRIN2BGRIN1NOS2SCN2A | |
| SCHEMBL17253944 | 0.78 | GRIN2B (0.69) | GRIN2BGRIN1NOS2 | |
| Hydrochloric Acid SCHEMBL4741316 | 0.77 | GRIN2B (0.67) | GRIN2BGRIN1 | |
| SCHEMBL5236050 | 0.76 | TSHR (0.52) | GRIN2BGRIN1 | |
| Terephthalic Acid SCHEMBL31728635 | 0.72 | LOXL2 (0.64) | — | |
| SCHEMBL11037096 | 0.72 | GRIN2B (0.56) | GRIN2BGRIN1NOS2SCN2A | |
| Terephthalic Acid SCHEMBL1887306 | 0.72 | TSHR (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777492-B1 | COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS | CHIRON CORP (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-0777492-A4 | COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS | CHIRON CORP (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0777492-A1 | COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS | CHIRON CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996040201-A1 | COMBINATORIAL LIBRARIES OF SUBSTRATE-BOUND CYCLIC ORGANIC COMPOUNDS | CHIRON CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |