Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037099 | 0.79 | GRIN2B (0.59) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL1230273 | 0.74 | NOS2 (0.67) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL11033759 | 0.74 | KMT2A (0.52) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL6136309 | 0.72 | GRIN2B (0.76) | GRIN2BGRIN1NOS2SCN2A | |
| Hydrochloric Acid SCHEMBL4003818 | 0.72 | NOS2 (0.64) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL456941 | 0.72 | GRIN2B (1.00) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL17196594 | 0.72 | GRIN2B (1.00) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL20806464 | 0.72 | GRIN2B (0.54) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL1158059 | 0.71 | CA12 (0.55) | — | |
| SCHEMBL45769 | 0.69 | GRIN2B (0.68) | GRIN2BGRIN1NOS2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59122459-A | — | — | None | — | — | JP | disclosed |
| JP-S59122459-A | BENZAMIDINE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | UBE IND LTD | 1984-07-14 | — | — | JP | disclosed |