Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767153 | 0.87 | L3MBTL1 (0.46) | ALDH1A1TBXAS1GAAL3MBTL1QPCT | |
| SCHEMBL941695 | 0.86 | TBXAS1 (0.56) | ALDH1A1TBXAS1ABL1RIN1 | |
| SCHEMBL14499226 | 0.85 | TBXAS1 (0.60) | ALDH1A1TBXAS1KDM4EABL1RIN1 | |
| SCHEMBL9716291 | 0.83 | TBXAS1 (0.63) | ALDH1A1TBXAS1ABL1RIN1 | |
| SCHEMBL11572618 | 0.83 | TBXAS1 (0.63) | ALDH1A1TBXAS1ABL1RIN1 | |
| SCHEMBL47374 | 0.83 | TBXAS1 (0.59) | ALDH1A1TBXAS1KDM4EABL1RIN1 | |
| SCHEMBL7818459 | 0.81 | TBXAS1 (0.52) | ALDH1A1TBXAS1GAAABL1RIN1 | |
| SCHEMBL14532409 | 0.80 | L3MBTL1 (0.55) | ALDH1A1TBXAS1L3MBTL1QPCT | |
| SCHEMBL7824835 | 0.80 | TBXAS1 (0.55) | ALDH1A1TBXAS1ABL1RIN1 | |
| SCHEMBL800961 | 0.78 | GAA (0.62) | ALDH1A1GAAL3MBTL1QPCTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |