Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136518 | 1.00 | RAB9A (0.45) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL5689580 | 0.76 | RAB9A (0.45) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL5689585 | 0.76 | RAB9A (0.45) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6136724 | 0.76 | RAB9A (0.45) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8425155 | 0.75 | PTK2 (0.54) | RAB9AKDM4EKMT2APTK2CYP1A2 | |
| SCHEMBL6934702 | 0.73 | GAA (0.48) | ALDH1A1LMNAKMT2ACYP1A2GAA | |
| SCHEMBL31267199 | 0.69 | HSD17B10 (0.51) | KDM4EKMT2APTK2CYP1A2GAA | |
| SCHEMBL31267203 | 0.69 | HSD17B10 (0.51) | KDM4EKMT2APTK2CYP1A2GAA | |
| SCHEMBL423961 | 0.69 | RAB9A (0.75) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL29806032 | 0.68 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994105-B1 | 2-amino-pyridine intermediates for beta3-Adrenergic receptor agonists | PFIZER PROD INC (US) | 2005-12-14 | — | — | EP | disclosed |