Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162691 | 0.92 | EPHX1 (0.47) | HPGDALDH1A1MAPTACHEEPHX1 | |
| SCHEMBL10563632 | 0.92 | HPGD (0.41) | HPGDALDH1A1MEN1MAPTPKM | |
| SCHEMBL4430601 | 0.88 | EPHX1 (0.50) | HPGDALDH1A1MAPTACHEEPHX1 | |
| SCHEMBL5164102 | 0.84 | EPHX1 (0.56) | ALDH1A1ACHEEPHX1 | |
| SCHEMBL2942928 | 0.84 | EPHX1 (0.61) | ACHEEPHX1 | |
| SCHEMBL4882104 | 0.84 | EPHX1 (0.61) | ACHEEPHX1 | |
| SCHEMBL2912153 | 0.84 | ACHE (0.48) | HPGDALDH1A1MEN1KMT2AACHE | |
| SCHEMBL5162543 | 0.83 | EPHX1 (0.59) | ACHEEPHX1 | |
| SCHEMBL27727591 | 0.81 | KDM4E (0.40) | HPGDALDH1A1MEN1KMT2AACHE | |
| SCHEMBL10564570 | 0.80 | ALDH1A1 (0.45) | HPGDALDH1A1MAPTACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059289-B1 | Process for manufacture of N-alk(en)oxy(or aryloxy)carbonyl isothiocyanates and their derivatives in the presence of N,N-dialkylarylamine catalyst | BAYER AG (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1113010-B1 | A process for the manufacture of substituted triazolinones | BAYER AG (US) | 2003-10-08 | — | — | EP | disclosed |
| EP-1113010-A1 | A process for the manufacture of substituted triazolinones | Bayer Corporation (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6197971-B1 | CYCLIZATION REACTION OF THIONOCARBAMATE WITH HYDRAZINE; ALKYLATION; HERBICIDE CHEMICAL INTERMEDIATES | BAYER CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6184412-B1 | REACTING A CHLOROFORMATE WITH A THIOCYANATE IN AN AQUEOUS SOLVENT AND A CATALYTIC N,N-DIALKYLARYLAMINE TO PRODUCE A N-ALKOXY(OR ARYLOXY)CARBONYL ISOTHIOCYANATE INTERMEDIATE; CONVERTING TO AN N-ALKOXY(OR ARYLOXY)CARBONYL ISOTHIOCYANATE | BAYER CORPORATION | 2001-02-06 | — | — | US | disclosed |
| EP-1059289-A1 | Process for manufacture of N-alk(en)oxy(or aryloxy)carbonyl isothiocyanates and their derivatives in the presence of N,N-dialkylarylamine catalyst | Bayer Corporation (US) | 2000-12-13 | — | — | EP | disclosed |
| US-RE32827-E | RECOVERY OF METALS | AMERICAN CYANAMID (US) | 1989-01-10 | — | — | US | disclosed |
| US-4657688-A | FROTH FLOTATION FOR RECOVERING OF METAL VALUES FROM BASE METAL SULFIDE ORES | AMERICAN CYANAMID COMPANY (US) | 1987-04-14 | — | — | US | disclosed |
| US-4595493-A | Providing aqueous pulp slurry of ore particles, conditioning slurry with frothing agent and metal collector thionocarbamate, frothing, recovering sulfides | AMERICAN CYANAMID COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| US-4584097-A | Neutral hydrocarboxycarbonyl thionocarbamate sulfide collectors | AMERICAN CYANAMID COMPANY (US) | 1986-04-22 | — | — | US | disclosed |