Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136884 | 0.88 | RORC (0.66) | RORCRARGHPGDHTT | |
| SCHEMBL6137028 | 0.82 | RORC (0.59) | RORCRARGHPGDHTT | |
| Hydrochloric Acid SCHEMBL6136775 | 0.81 | RORC (0.57) | RORCRAB9ANPC1MAPTRARG | |
| Hydrochloric Acid SCHEMBL6136946 | 0.81 | RORC (0.57) | RORCRAB9ANPC1MAPTRARG | |
| SCHEMBL6136897 | 0.78 | RORC (0.54) | RORCKDM4ERARGMEN1KMT2A | |
| SCHEMBL6136876 | 0.78 | RORC (0.54) | RORCKDM4ERARGMEN1KMT2A | |
| SCHEMBL6136872 | 0.77 | RORC (0.47) | RORCRARGHPGDMEN1KMT2A | |
| SCHEMBL6137351 | 0.76 | RORC (0.50) | RORCRARGHPGD | |
| SCHEMBL6136923 | 0.75 | MAPK8 (0.55) | RORCRARGHPGDMEN1KMT2A | |
| SCHEMBL6137025 | 0.74 | F2RL3 (0.51) | RORCRARGHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140856-B1 | FLUORESCENT DYES FOR SOLID PHASE AND SOLUTION PHASE SCREENING | NOVARTIS AG (CH) | 2005-04-27 | — | — | EP | disclosed |
| EP-1140856-A1 | FLUORESCENT DYES FOR SOLID PHASE AND SOLUTION PHASE SCREENING | Novartis AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037448-A1 | FLUORESCENT DYES FOR SOLID PHASE AND SOLUTION PHASE SCREENING | NOVARTIS AG (CH) | 2000-06-29 | — | — | WO | disclosed |