Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136876 | 1.00 | RORC (0.54) | RORCTDP1PTPN11RARGMEN1 | |
| SCHEMBL6136884 | 0.89 | RORC (0.66) | RORCRARG | |
| SCHEMBL6137102 | 0.87 | PTPN11 (0.54) | RORCTDP1PTPN11RARGKDM4E | |
| SCHEMBL14290280 | 0.84 | RAB9A (0.53) | PTPN11MEN1KMT2APOLB | |
| SCHEMBL6137028 | 0.83 | RORC (0.59) | RORCRARG | |
| SCHEMBL6137111 | 0.82 | PTPN11 (0.50) | TDP1PTPN11RARG | |
| Hydrochloric Acid SCHEMBL6136775 | 0.82 | RORC (0.57) | RORCRARG | |
| Hydrochloric Acid SCHEMBL6136946 | 0.82 | RORC (0.57) | RORCRARG | |
| SCHEMBL6136871 | 0.78 | RORC (0.53) | RORCRARGMEN1KMT2AKDM4E | |
| SCHEMBL6137351 | 0.77 | RORC (0.50) | RORCRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140856-B1 | FLUORESCENT DYES FOR SOLID PHASE AND SOLUTION PHASE SCREENING | NOVARTIS AG (CH) | 2005-04-27 | — | — | EP | disclosed |
| EP-1140856-A1 | FLUORESCENT DYES FOR SOLID PHASE AND SOLUTION PHASE SCREENING | Novartis AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037448-A1 | FLUORESCENT DYES FOR SOLID PHASE AND SOLUTION PHASE SCREENING | NOVARTIS AG (CH) | 2000-06-29 | — | — | WO | disclosed |