Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704965 | 0.89 | KDM4E (0.44) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7800663 | 0.86 | MAPT (0.39) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL7809809 | 0.85 | MAPT (0.41) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL6136935 | 0.78 | PDE10A (0.55) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL1380105 | 0.77 | PDE10A (0.42) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7800903 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AHPGDRECQL | |
| SCHEMBL1380335 | 0.75 | KDM4E (0.43) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL6137031 | 0.74 | CA1 (0.50) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30238017 | 0.74 | PTK2 (0.42) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL6136919 | 0.74 | ERN1 (0.38) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153917-B1 | p-Aminophenol derivatives and colorants containing them | WELLA AG (DE) | 2005-04-13 | — | — | EP | claimed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | claimed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | claimed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | claimed |
| EP-1153917-B1 | p-Aminophenol derivatives and colorants containing them | WELLA AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | disclosed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | disclosed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | KRT18, AASDHPPT, S100P | ALDH1A1 99/4885KDM4E 354/4885MEN1 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.