Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704834 | 0.89 | KDM4E (0.40) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL7457120 | 0.86 | MAPT (0.36) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL6136914 | 0.77 | ALDH1A1 (0.41) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL1378405 | 0.77 | PDE10A (0.52) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL7456111 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AEIF4EBCAT2 | |
| SCHEMBL1381854 | 0.74 | PDE10A (0.40) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL6288457 | 0.73 | CA1 (0.47) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL1380335 | 0.73 | KDM4E (0.43) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| Ethane SCHEMBL28807032 | 0.73 | PDE10A (0.65) | PDE10AKDM4EALDH1A1CASP1ALOX15 | |
| SCHEMBL30880219 | 0.73 | PDE10A (0.64) | PDE10AKDM4EALDH1A1CASP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4785024-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| US-6840965-B2 | P-aminophenols and colorants containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | claimed |
| EP-1222166-B1 | NOVEL P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2003-08-13 | — | — | EP | claimed |
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | claimed |
| EP-1222166-A2 | NOVEL P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-07-17 | — | — | EP | claimed |
| WO-2001085683-A2 | PYRROLYL-, FURANYL- AND THIENYL-SUBSTITUTED P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | claimed |
| US-6840965-B2 | P-aminophenols and colorants containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |
| EP-1222166-B1 | NOVEL P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2003-08-13 | — | — | EP | disclosed |
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| EP-1222166-A2 | NOVEL P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001085683-A2 | PYRROLYL-, FURANYL- AND THIENYL-SUBSTITUTED P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | ALPP, GSTP1, GPX4 | PDE10A 1900/4885KDM4E 1805/4885ALDH1A1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.