Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648692 | 0.90 | MAOA (0.55) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL12118723 | 0.86 | MAOA (0.63) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL13177821 | 0.85 | MAPT (0.58) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL1733547 | 0.83 | MAPT (0.48) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL18475023 | 0.81 | CYP1A2 (0.51) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL13609808 | 0.81 | CYP1A2 (0.44) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL595104 | 0.81 | P2RY12 (0.56) | CYP1A2TSHRMEN1KMT2AMAPT | |
| SCHEMBL1993795 | 0.80 | MAOA (0.72) | CYP1A2MAOAMEN1KMT2AMAPT | |
| SCHEMBL18295496 | 0.80 | ALDH1A1 (0.43) | CYP1A2TSHRMAOAMEN1KMT2A | |
| SCHEMBL11125302 | 0.80 | CYP1A2 (0.53) | CYP1A2TSHRMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2926967-B1 | SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2025-10-08 | — | — | EP | disclosed |
| US-10241234-B2 | Silicone hydrogel soft contact lens having wettable surface | HOYA CORPORATION (JP) | 2019-03-26 | — | — | US | disclosed |
| US-9529119-B2 | Method for fabricating silicone-containing copolymer molded article having hydrophilic surface and silicone-hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20160282516-A1 | METHOD FOR FABRICATING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE AND SILICONE-HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-2840431-B1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORP (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2845708-B1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2016-07-06 | — | — | EP | disclosed |
| CN-103959140-B | There is the silicone hydrogels soft contact lens of wettable surface | HOYA CORP. (JP) | 2016-05-04 | — | — | CN | disclosed |
| EP-2926967-A1 | Silicone hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2015-10-07 | — | — | EP | disclosed |
| CN-104602886-A | Method for fabricating silicone-containing copolymer molded article having hydrophilic surface and silicone hydrogel contact lens having hydrophilic surface | HOYA CORP | 2015-05-06 | — | — | CN | disclosed |
| EP-2845708-A1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| EP-2840431-A1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORPORATION (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-20140362339-A1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORPORATION (JP) | 2014-12-11 | — | — | US | disclosed |
| CN-103959140-A | Silicone hydrogel soft contact lens having wettable surface | HOYA CORP | 2014-07-30 | — | — | CN | disclosed |
| EP-1128191-B1 | Materials for contact lenses comprising a macromer having the polysiloxane structure in the side chain | HOYA HEALTHCARE CORP (JP) | 2005-04-20 | — | — | EP | disclosed |
| US-6602930-B2 | Excellent flexibility and oxygen permeability | HOYA HEALTHCARE CORPORATION (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-0823643-B1 | Soft contact lens with high moisture content and method for producing the same | HOYA CORP (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-20020005933-A1 | Materials for contact lenses comprising a macromer having the polysiloxane structure in the side chain | HOYA CORPORATION (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-1128191-A2 | Materials for contact lenses comprising a macromer having the polysiloxane structure in the side chain | HOYA HEALTHCARE CORPORATION (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-5965630-A | POLYMERIZING HYDROPHILIC MONOMERS, HYDROXYETHYL METHACRYLATE, VINYL-2-PYRROLIDONE, DIMETHYLACRYLAMIDE, AN ALKYL METHACRYLATE AND A CROSSLINKER IN A DILUENT OF TRIETHYLENE GLYCOL, DI- OR TRIETHYLENE GLYCOL MONOMETHYL ETHER | HOYA CORPORATION (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0823643-A1 | Soft contact lens with high moisture content and method for producing the same | HOYA CORPORATION (JP) | 1998-02-11 | — | — | EP | disclosed |