Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | TERT | O14746 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137259 | 0.90 | CYP1A2 (0.52) | MAOATERTMEN1KMT2AMMP14 | |
| SCHEMBL1993795 | 0.89 | MAOA (0.72) | MAOATERTMEN1KMT2APOLB | |
| SCHEMBL373676 | 0.87 | MAOA (0.64) | MAOATERTMEN1KMT2APOLB | |
| SCHEMBL10430973 | 0.85 | MAOA (0.51) | MAOATERTMEN1KMT2AMMP14 | |
| SCHEMBL6370986 | 0.82 | MAOA (0.77) | MAOATERTMEN1KMT2AMMP14 | |
| SCHEMBL13177817 | 0.80 | CYP19A1 (0.44) | MAOAMEN1KMT2ARXFP1NSD2 | |
| SCHEMBL13177827 | 0.80 | CYP19A1 (0.44) | MAOAMEN1KMT2ARXFP1NSD2 | |
| SCHEMBL18295496 | 0.80 | ALDH1A1 (0.43) | MAOATERTMEN1KMT2ARXFP1 | |
| SCHEMBL13177821 | 0.80 | MAPT (0.58) | MAOAMEN1KMT2ARXFP1POLB | |
| SCHEMBL1071678 | 0.79 | MEN1 (0.57) | MAOATERTMEN1KMT2AMMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119753-B2 | Silicone hydrogels with amino surface groups | BAUSCH & LOMB INCORPORATED (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090103045-A1 | SILICONE HYDROGELS WITH AMINO SURFACE GROUPS | SALIX PHARMACEUTICALS, INC. | 2009-04-23 | — | — | US | disclosed |
| US-20070264503-A1 | Polymers comprising polyhydric alcohols, medical devices modified with same, and method of making | BAUSCH & LOMB INCORPORATED | 2007-11-15 | — | — | US | disclosed |
| US-20070264509-A1 | Copolymer and Medical Device with the Copolymer | BAUSCH & LOMB INCORPORATED | 2007-11-15 | — | — | US | disclosed |