Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895402 | 0.77 | PPARD (0.40) | — | |
| SCHEMBL6609298 | 0.77 | LTA4H (0.44) | LTA4HMKNK1 | |
| SCHEMBL13093384 | 0.76 | TAAR1 (0.46) | LTA4HMKNK1 | |
| Hydrochloric Acid SCHEMBL2880210 | 0.75 | TAAR1 (0.44) | LTA4HMKNK1 | |
| SCHEMBL28801523 | 0.75 | CA12 (0.41) | — | |
| SCHEMBL7286795 | 0.73 | ARG1 (0.34) | — | |
| SCHEMBL11722232 | 0.72 | MKNK1 (0.33) | MKNK1 | |
| SCHEMBL9432433 | 0.72 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL5662351 | 0.71 | ARG1 (0.34) | — | |
| SCHEMBL29197763 | 0.71 | KDM1A (0.39) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453816-A4 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1453816-A2 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003045306-A2 | PHENOXY AMINE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2003-06-05 | — | — | WO | disclosed |