Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313142 | 0.68 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL2421174 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL2418988 | 0.63 | ESR2 (0.68) | ESR1ESR2 | |
| SCHEMBL6137646 | 0.61 | ESR2 (0.30) | ESR1ESR2 | |
| SCHEMBL3645124 | 0.60 | BCL2 (0.30) | — | |
| SCHEMBL2417367 | 0.58 | SHBG (0.41) | ESR1ESR2 | |
| SCHEMBL3642220 | 0.58 | AR (0.30) | — | |
| SCHEMBL24899283 | 0.57 | L3MBTL1 (0.33) | — | |
| SCHEMBL6137841 | 0.56 | CRBN (0.32) | — | |
| SCHEMBL27340117 | 0.54 | ELANE (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257264-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1257264-A1 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001082923-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2001-11-08 | — | — | WO | disclosed |