Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418579 | 0.90 | ESR2 (0.35) | ESR2ESR1 | |
| SCHEMBL6137326 | 0.86 | ESR1 (0.37) | ESR2ESR1 | |
| SCHEMBL2421174 | 0.79 | KDM4E (0.33) | — | |
| SCHEMBL6313142 | 0.72 | ESR1 (0.32) | ESR2ESR1 | |
| SCHEMBL6137646 | 0.71 | ESR2 (0.30) | ESR2ESR1 | |
| SCHEMBL2417367 | 0.71 | SHBG (0.41) | ESR2ESR1 | |
| SCHEMBL6137378 | 0.64 | — | — | |
| SCHEMBL2416850 | 0.61 | ESR2 (0.66) | ESR2ESR1 | |
| SCHEMBL7137052 | 0.58 | HSD17B1 (0.40) | ESR2ESR1 | |
| SCHEMBL2417031 | 0.57 | ESR2 (0.65) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257264-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1257264-A1 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001082923-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2001-11-08 | — | — | WO | disclosed |