SCHEMBL6137763

SCHEMBL6137763

CN(C(=O)CCOc1ccccc1)c1ccccc1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
PAX8 Q06710 1/20 0.46
LTA4H P09960 1/20 0.46
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TSHR P16473 2/20 0.43
TP53 P04637 2/20 0.43
NPC1 O15118 3/20 0.43
LMNA P02545 2/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10272367 0.79 ALDH1A1 (0.48) ALDH1A1TSHRTP53
SCHEMBL6138794 0.78 KMT2A (0.50) ALOX5ALDH1A1MAPTHTTPAX8
SCHEMBL8979642 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTP53NPC1LMNA
SCHEMBL1115146 0.77 HDAC3 (0.44) ALOX5ALDH1A1MAPTTSHRTP53
SCHEMBL1114942 0.77 HDAC3 (0.44) ALOX5ALDH1A1MAPTTSHRTP53
SCHEMBL31287485 0.76 ALDH1A1 (0.44) ALDH1A1TSHRTP53RAB9A
SCHEMBL307587 0.75 ALDH1A1 (0.43) ALDH1A1MAPTTSHRTP53NPC1
SCHEMBL11339370 0.75 ALDH1A1 (0.44) ALDH1A1MAPTTSHRTP53MAPK1
SCHEMBL13684202 0.75 ALDH1A1 (0.47) ALDH1A1MAPTTSHRTP53MAPK1
SCHEMBL12679936 0.74 ALOX5 (0.40) ALOX5ALDH1A1MAPTTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269906-A Process for the preparation of optically active (R) -phenoxypropionic acid-N-methyl-N-2-fluorophenylamide 安徽赛乐普制药有限公司 2020-06-12 CN claimed
US-20050043180-A1 For prevention of generation of barnyard grass produced from rice DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2005-02-24 US claimed
EP-1448058-A4 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES DONGBU HANNONG CHEMICAL CO LTD (KR) 2005-01-26 EP claimed
EP-1448058-A1 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES Dongbu Hannong Chemical Co., Ltd. (KR) 2004-08-25 EP claimed
WO-2003037085-A1 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2003-05-08 WO claimed
CN-111269906-A Process for the preparation of optically active (R) -phenoxypropionic acid-N-methyl-N-2-fluorophenylamide 安徽赛乐普制药有限公司 2020-06-12 CN disclosed
CN-111269906-A Process for the preparation of optically active (R) -phenoxypropionic acid-N-methyl-N-2-fluorophenylamide 安徽赛乐普制药有限公司 2020-06-12 CN disclosed
CN-111269906-A Process for the preparation of optically active (R) -phenoxypropionic acid-N-methyl-N-2-fluorophenylamide 安徽赛乐普制药有限公司 2020-06-12 CN disclosed
CN-1279031-C Optically active herbicidal (R)-phenoxypropionic acid-N-methyl-N-2-fluorophenyl amides DONGBU HANNONG CHEMICAL CO LTD (KR) 2006-10-11 CN disclosed
CN-1279031-C Optically active herbicidal (R)-phenoxypropionic acid-N-methyl-N-2-fluorophenyl amides DONGBU HANNONG CHEMICAL CO LTD (KR) 2006-10-11 CN disclosed
US-20050043180-A1 For prevention of generation of barnyard grass produced from rice DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2005-02-24 US disclosed
US-20050043180-A1 For prevention of generation of barnyard grass produced from rice DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2005-02-24 US disclosed
EP-1448058-A4 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES DONGBU HANNONG CHEMICAL CO LTD (KR) 2005-01-26 EP disclosed
CN-1558717-A Optically active (R) -phenoxypropionic acid-N-methyl-N-2-fluorophenylamide compounds having herbicidal activity ������ũ��ѧ��ʽ���� 2004-12-29 CN disclosed
CN-1558717-A Optically active (R) -phenoxypropionic acid-N-methyl-N-2-fluorophenylamide compounds having herbicidal activity ������ũ��ѧ��ʽ���� 2004-12-29 CN disclosed
EP-1448058-A1 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES Dongbu Hannong Chemical Co., Ltd. (KR) 2004-08-25 EP disclosed
WO-2003037085-A1 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2003-05-08 WO disclosed
WO-2003037085-A1 OPTICALLY ACTIVE HERBICIDAL (R)-PHENOXYPROPIONIC ACID-N-METHYL-N-2-FLUOROPHENYL AMIDES DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2003-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043180-A1 For prevention of generation of barnyard grass produced from rice CBR3, HRH3, H1-3 ALOX5 486/4885ALDH1A1 1553/4885MAPT 4698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.