Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8767719 | 0.73 | CA1 (0.45) | MAPT | |
| SCHEMBL1283890 | 0.72 | L3MBTL1 (0.61) | MAPTTHRB | |
| SCHEMBL1284112 | 0.72 | L3MBTL1 (0.59) | THRB | |
| SCHEMBL9373815 | 0.72 | MMP2 (0.50) | — | |
| SCHEMBL4628766 | 0.71 | NPC1 (0.61) | MAPT | |
| SCHEMBL6137598 | 0.71 | DRD2 (0.53) | MAPT | |
| SCHEMBL4628771 | 0.70 | SCN5A (0.70) | — | |
| SCHEMBL18542248 | 0.70 | TSHR (0.58) | TP53MAPT | |
| SCHEMBL6323761 | 0.70 | L3MBTL1 (0.52) | MAPTTHRBPTGIRMAOAMAOB | |
| SCHEMBL6137840 | 0.69 | SCN5A (0.49) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032556-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE INC (US) | 2005-02-02 | — | — | EP | disclosed |
| EP-1032556-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999020599-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-04-29 | — | — | WO | disclosed |