Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137727 | 0.90 | NQO2 (0.34) | MKNK1NR4A2LMNASMN1; SMN2KMT2A | |
| SCHEMBL6137710 | 0.81 | DPP4 (0.44) | LMNASMN1; SMN2TDP1GAAHTT | |
| SCHEMBL13601850 | 0.78 | NQO2 (0.39) | MKNK1SMN1; SMN2KMT2AGAAKDM4E | |
| SCHEMBL6137870 | 0.76 | NR4A2 (0.40) | NR4A2LMNASMN1; SMN2TSHRGAA | |
| SCHEMBL536590 | 0.72 | KDM4E (0.46) | MKNK1NR4A2LMNAKMT2ATDP1 | |
| SCHEMBL543109 | 0.71 | PLA2G2A (0.44) | NR4A2LMNASMN1; SMN2KMT2ATSHR | |
| Potassium SCHEMBL29729324 | 0.71 | KDM4E (0.45) | MKNK1NR4A2LMNAKMT2ATDP1 | |
| SCHEMBL31732891 | 0.70 | MKNK1 (0.36) | MKNK1NR4A2KMT2ACA12CA1 | |
| SCHEMBL7348969 | 0.70 | PARP1 (0.37) | SMN1; SMN2TSHRHTTKDM4EALDH1A1 | |
| SCHEMBL1081072 | 0.70 | HPGD (0.35) | MKNK1LMNASMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515956-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1515956-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Smithkline Beecham (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003104209-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |