Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137875 | 0.81 | MKNK1 (0.39) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL10713223 | 0.81 | KDM4E (0.37) | ALDH1A1KDM4EHSD17B10KDM5AKDM4C | |
| SCHEMBL30798651 | 0.79 | PARP1 (0.37) | ALDH1A1KDM4EHSD17B10KDM5APARP1 | |
| SCHEMBL18226070 | 0.79 | PARP1 (0.37) | ALDH1A1KDM4EHSD17B10KDM5APARP1 | |
| SCHEMBL4535251 | 0.74 | CSNK2A1 (0.39) | DPP4ALDH1A1KDM4EDYRK1APARP1 | |
| SCHEMBL29805281 | 0.74 | CSNK2A1 (0.39) | DPP4ALDH1A1KDM4EDYRK1APARP1 | |
| SCHEMBL6137727 | 0.72 | NQO2 (0.34) | ALDH1A1KDM4EHSD17B10HTTHPGD | |
| SCHEMBL6137705 | 0.72 | DPP4 (0.48) | DPP4ALDH1A1KDM4EHSD17B10KDM5A | |
| SCHEMBL30028461 | 0.72 | KDM4E (0.47) | ALDH1A1KDM4EKDM5AKDM4CPARP1 | |
| SCHEMBL7348969 | 0.71 | PARP1 (0.37) | ALDH1A1KDM4EHSD17B10DYRK1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515956-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1515956-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Smithkline Beecham (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003104209-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |