Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.74 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994928 | 0.87 | LTB4R (0.84) | LTB4RLTB4R2MAPTPLA2G4BLMNA | |
| SCHEMBL8203909 | 0.86 | LTB4R (0.69) | LTB4RLTB4R2MCHR1TSHRBCL2L1 | |
| SCHEMBL8994956 | 0.86 | LTB4R (0.72) | LTB4RLTB4R2TSHRRENHTR1A | |
| SCHEMBL8748088 | 0.86 | LTB4R (0.72) | LTB4RLTB4R2MAPTPLA2G4BPPARD | |
| SCHEMBL8747939 | 0.85 | LTB4R (0.74) | LTB4RLTB4R2MAPTPLA2G4BPPARD | |
| Moxilubant SCHEMBL29388138 | 0.85 | LTB4R (1.00) | LTB4RLTB4R2PLA2G4BHTR2AADRA1A | |
| Moxilubant SCHEMBL6439215 | 0.85 | LTB4R (1.00) | LTB4RLTB4R2PLA2G4BHTR2AADRA1A | |
| SCHEMBL8748091 | 0.85 | LTB4R (0.74) | LTB4RLTB4R2MAPTPLA2G4BPPARD | |
| SCHEMBL8074983 | 0.85 | LTB4R (0.67) | LTB4RLTB4R2MCHR1TSHRBCL2L1 | |
| SCHEMBL9121783 | 0.85 | LTB4R (0.70) | LTB4RLTB4R2MCHR1MAPTPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451163-A4 | 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | DONG WHA PHARM IND CO LTD (KR) | 2005-01-26 | — | — | EP | disclosed |
| EP-1451163-A1 | 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003040113-A1 | 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | DONG WHA PHARM. IND. CO., LTD. (KR) | 2003-05-15 | — | — | WO | disclosed |