Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.69 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994956 | 0.90 | LTB4R (0.72) | LTB4RLTB4R2PRSS1THRATHRB | |
| SCHEMBL8074983 | 0.89 | LTB4R (0.67) | LTB4RLTB4R2PRSS1THRATHRB | |
| SCHEMBL6138115 | 0.86 | LTB4R (0.74) | LTB4RLTB4R2TSHRBCL2L1MCHR1 | |
| SCHEMBL8994928 | 0.83 | LTB4R (0.84) | LTB4RLTB4R2PRSS1THRATHRB | |
| SCHEMBL1545763 | 0.83 | THRA (0.51) | LTB4RPRSS1THRATHRBTSHR | |
| SCHEMBL8748088 | 0.83 | LTB4R (0.72) | LTB4RLTB4R2PRSS1THRATHRB | |
| Moxilubant SCHEMBL6439215 | 0.82 | LTB4R (1.00) | LTB4RLTB4R2PRSS1 | |
| SCHEMBL8747939 | 0.82 | LTB4R (0.74) | LTB4RLTB4R2PRSS1THRATHRB | |
| SCHEMBL8748091 | 0.82 | LTB4R (0.74) | LTB4RLTB4R2PRSS1THRATHRB | |
| Moxilubant SCHEMBL29388138 | 0.82 | LTB4R (1.00) | LTB4RLTB4R2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150390-A | ACCELERATES BONE FORMATION; OSTEOPOROSIS; (LTB-4(LEUKOTRIENE-B-4; 5,12-DIHYDROXYEICOSATETRA-6,8,10,14-ENOIC ACID) RECEPTOR ANTAGONIST | DONG WHA PHARM. IND. CO., LTD. (KR) | 2000-11-21 | — | — | US | disclosed |