Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17196034 | 0.77 | LOXL2 (0.39) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL3187102 | 0.77 | CALM1 (0.55) | IDH1KDM4EMEN1POLBGAA | |
| SCHEMBL19315909 | 0.76 | TRPA1 (0.42) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL564637 | 0.76 | KDM4E (0.80) | IDH1KDM4EMEN1POLBGAA | |
| SCHEMBL25049607 | 0.75 | KDM4E (0.37) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL6138207 | 0.75 | GAA (0.48) | IDH1KDM4EMEN1POLBGAA | |
| SCHEMBL15589681 | 0.73 | MAOB (0.53) | GAAMAPTRAB9ACYP3A4 | |
| SCHEMBL20961910 | 0.73 | SKP2 (0.44) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL7285039 | 0.72 | CALM1 (0.48) | IDH1KDM4EMEN1POLBGAA | |
| SCHEMBL6351215 | 0.72 | CYP3A4 (0.80) | IDH1KDM4EMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215525-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |