Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139310 | 0.91 | ALDH1A1 (0.41) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL6139180 | 0.85 | PELI1 (0.46) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL6139083 | 0.81 | AURKA (0.37) | ALDH1A1SMN1; SMN2LMNAPTGS2HPGD | |
| SCHEMBL6139321 | 0.80 | PELI1 (0.50) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL6139324 | 0.80 | PELI1 (0.50) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL6139166 | 0.79 | PELI1 (0.43) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL6139157 | 0.79 | MAPT (0.44) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL6098062 | 0.79 | PELI1 (0.65) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| Hydrochloric Acid SCHEMBL6139155 | 0.79 | PELI1 (0.49) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 | |
| Hydrochloric Acid SCHEMBL6139158 | 0.79 | PELI1 (0.49) | PELI1ALDH1A1SMN1; SMN2LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263712-B1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
| EP-1263712-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002074731-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | PELI1 2908/4885ALDH1A1 31/4885SMN1; SMN2 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.