SCHEMBL6138836

SCHEMBL6138836

C=C(C)c1cccc(O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ADAMTS4 O75173 1/20 0.50
EGFR P00533 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
FYN P06241 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MMP8 P22894 1/20 0.50
CA6 P23280 1/20 0.50
CDK2 P24941 1/20 0.50
MMP12 P39900 1/20 0.50
RECQL P46063 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ADAMTS5 Q9UNA0 1/20 0.50
TRPA1 O75762 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrogallol SCHEMBL9475780 0.88 ALDH1A1 (0.55) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL5443939 0.87 ALDH1A1 (0.39) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL9743448 0.83 SELL (0.50) ALDH1A1HPGDALOX15HSD17B10RECQL
SCHEMBL524038 0.83 CDK2 (0.40) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL29349932 0.80 KMT2A (0.56) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL208880 0.80 KMT2A (0.56) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL27516051 0.80 KMT2A (0.56) ALDH1A1LMNAHPGDALOX15HSD17B10
Pyrogallol SCHEMBL2266603 0.79 ALDH1A1 (0.71) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL29473783 0.79 TRPA1 (0.50) ALDH1A1LMNAHPGDALOX15HSD17B10
SCHEMBL685070 0.79 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10TRPA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1099691-B1 N-Sulfonyloxyimide compound and radiation-sensitive resin composition using the same JSR CORP (JP) 2005-03-02 EP claimed
EP-0819981-B1 Radiation sensitive resin composition JSR CORP (JP) 2002-06-05 EP claimed
EP-0435418-B1 A dispersant/antioxidant viscosity index improving lubricant additive TEXACO DEVELOPMENT CORP (US) 1995-01-04 EP claimed
US-20110091807-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-20110091807-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-4366328-A HEAT DECOMPOSITION OF A 1,1,3-TRIMETHYL, 3-HYDROXYPHENYL, HYDROXYINDANE USING AN ACID OR BASIC CATALYST; DEARYLATION; AROMATIZATION MITSUI TOATSU CHEMICALS, INC. (JP) 1982-12-28 US disclosed
US-4298720-A HEAT RESISTANT MOLDING MATERIALS AND VULCANIZATION ACCELERATORS MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1981-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091807-A1 PHOTORESIST COMPOSITION H1-0, H1-2, H1-3 ALDH1A1 1807/4885LMNA 1512/4885HPGD 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.