Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138836 | 0.83 | ALDH1A1 (0.50) | CDK2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL5443939 | 0.80 | ALDH1A1 (0.39) | CDK2ALDH1A1HPGDHSD17B10KDM4E | |
| Pyrogallol SCHEMBL9475780 | 0.77 | ALDH1A1 (0.55) | CDK2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL12827332 | 0.75 | DBH (0.48) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL208880 | 0.73 | KMT2A (0.56) | ALDH1A1HPGDHSD17B10KDM4EALOX15 | |
| SCHEMBL29349932 | 0.73 | KMT2A (0.56) | ALDH1A1HPGDHSD17B10KDM4EALOX15 | |
| SCHEMBL27516051 | 0.73 | KMT2A (0.56) | ALDH1A1HPGDHSD17B10KDM4EALOX15 | |
| SCHEMBL344192 | 0.73 | ALDH1A1 (0.61) | CDK2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL29473783 | 0.72 | TRPA1 (0.50) | CDK2ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL685070 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130209386-A1 | NEW USES | EVOCUTIS PLC (GB) | 2013-08-15 | — | — | US | disclosed |
| EP-2598208-A2 | NEW USES | Evocutis plc (GB) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012172318-A1 | FORMULATIONS CONTAINING TROPOLONOIDS, COPPER SALT AND A SOLVENT SYSTEM | EVOCUTIS PLC (GB) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012013967-A2 | NEW USES | SYNTOPIX GROUP PLC (GB) | 2012-02-02 | — | — | WO | disclosed |