Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.33 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139166 | 0.91 | PELI1 (0.43) | ALDH1A1PTGS2KDM4EHPGDLY96 | |
| SCHEMBL6139299 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SLC6A19PTGS1PTGS2MAP3K7 | |
| SCHEMBL6139142 | 0.83 | AURKA (0.38) | ALDH1A1PTGS2HPGDSMN1; SMN2GAA | |
| SCHEMBL6138958 | 0.83 | KDM1A (0.43) | ALDH1A1KDM4EMCHR1SMN1; SMN2NPC1 | |
| SCHEMBL452549 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SLC6A19PTGS1PTGS2MAP3K7 | |
| SCHEMBL452551 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SLC6A19PTGS1PTGS2MAP3K7 | |
| SCHEMBL6139310 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SLC6A19PTGS1PTGS2MAP3K7 | |
| SCHEMBL6094482 | 0.78 | PELI1 (0.51) | ALDH1A1SLC6A19KDM4EHPGDPELI1 | |
| SCHEMBL6094479 | 0.78 | PELI1 (0.51) | ALDH1A1SLC6A19KDM4EHPGDPELI1 | |
| Hydrochloric Acid SCHEMBL6139401 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SLC6A19PTGS1PTGS2MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263712-B1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
| EP-1263712-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002074731-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | ALDH1A1 31/4885SLC6A19 1349/4885PTGS1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.