Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MMP9 | P14780 | 8/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139051 | 1.00 | KDM1A (0.56) | KDM1ADDX3XALDH1A1MAOBMAPT | |
| Hydrochloric Acid SCHEMBL6138948 | 0.99 | KDM1A (0.55) | KDM1ADDX3XALDH1A1MAOBMAPT | |
| Hydrochloric Acid SCHEMBL6138951 | 0.99 | KDM1A (0.55) | KDM1ADDX3XALDH1A1MAOBMAPT | |
| SCHEMBL6095328 | 0.91 | MMP1 (0.56) | KDM1ADDX3XMAOBMAPTNPC1 | |
| SCHEMBL6095335 | 0.91 | MMP1 (0.56) | KDM1ADDX3XMAOBMAPTNPC1 | |
| SCHEMBL6097007 | 0.87 | KDM1A (0.65) | KDM1ADDX3XALDH1A1MAOBMAPT | |
| SCHEMBL6097012 | 0.87 | KDM1A (0.65) | KDM1ADDX3XALDH1A1MAOBMAPT | |
| SCHEMBL6138676 | 0.87 | SNCA (0.51) | KDM1AMAOBMAPTNPC1RAB9A | |
| SCHEMBL6138679 | 0.87 | SNCA (0.51) | KDM1AMAOBMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6094703 | 0.86 | KDM1A (0.63) | KDM1ADDX3XALDH1A1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263712-B1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
| EP-1263712-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002074731-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | KDM1A 3571/4885DDX3X 733/4885ALDH1A1 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.