Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 3/20 | 0.41 |
| ▸ | FLT4 | P35916 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824902 | 1.00 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2169427 | 0.92 | ABCB11 (0.39) | MEN1KMT2AABCB11ALDH1A1LMNA | |
| SCHEMBL28560399 | 0.92 | ABCB11 (0.39) | MEN1KMT2AABCB11ALDH1A1LMNA | |
| SCHEMBL26301826 | 0.92 | ABCB11 (0.39) | MEN1KMT2AABCB11ALDH1A1LMNA | |
| SCHEMBL28555501 | 0.91 | LMNA (0.42) | MEN1KMT2AABCB11ALDH1A1LMNA | |
| SCHEMBL28566525 | 0.90 | GCKR (0.44) | FLT1FLT4KDRKMT2AALDH1A1 | |
| SCHEMBL14141639 | 0.87 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL29993001 | 0.87 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL23524 | 0.87 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL7490542 | 0.85 | TDP1 (0.43) | FLT1FLT4KDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894186-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-SYNTHELABO (FR) | 2005-05-17 | — | — | US | claimed |