Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993001 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1POLBVDRHSP90AA1 | |
| SCHEMBL14141639 | 1.00 | KMT2A (0.44) | KMT2AALDH1A1POLBVDRHSP90AA1 | |
| SCHEMBL5120356 | 0.87 | HSD11B1 (0.43) | KMT2AALDH1A1VDRHSP90AA1P2RY2 | |
| SCHEMBL31316 | 0.87 | HSD11B1 (0.43) | KMT2AALDH1A1VDRHSP90AA1P2RY2 | |
| SCHEMBL14141983 | 0.87 | HSD11B1 (0.43) | KMT2AALDH1A1VDRHSP90AA1P2RY2 | |
| SCHEMBL31317 | 0.87 | HSD11B1 (0.43) | KMT2AALDH1A1VDRHSP90AA1P2RY2 | |
| SCHEMBL6139230 | 0.87 | PSEN1 (0.43) | KMT2AALDH1A1LMNAF2PRSS1 | |
| SCHEMBL28824902 | 0.87 | PSEN1 (0.43) | KMT2AALDH1A1LMNAF2PRSS1 | |
| SCHEMBL2169427 | 0.86 | ABCB11 (0.39) | KMT2AALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL28560399 | 0.86 | ABCB11 (0.39) | KMT2AALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928251-B | Preparation method of high-purity clopidogrel | 江苏天士力帝益药业有限公司 | 2021-05-04 | — | — | CN | claimed |
| US-7329751-B2 | Process for the preparation of clopidogrel | DIPHARMA S.P.A. (IT) | 2008-02-12 | — | — | US | claimed |
| EP-1501838-B1 | A PROCESS FOR THE PREPARATION OF CLOPIDOGREL | DIPHARMA FRANCIS SRL (IT) | 2007-04-11 | — | — | EP | claimed |
| US-20050143414-A1 | Process for the preparation of clopidogrel | DIPHARMA S.P.A. (IT) | 2005-06-30 | — | — | US | claimed |
| US-6894186-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-SYNTHELABO (FR) | 2005-05-17 | — | — | US | claimed |
| EP-1501838-A1 | A PROCESS FOR THE PREPARATION OF CLOPIDOGREL | Dinamite Dipharma S.p.A. (in abbreviated form Dipharma S.p.A.) (IT) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093276-A1 | A PROCESS FOR THE PREPARATION OF CLOPIDOGREL | DIPHARMA S.P.A. (IT) | 2003-11-13 | — | — | WO | claimed |
| CN-112778371-B | Thienopyridine derivative and preparation method and application thereof | 华创合成制药股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11834413-B2 | Antiplatelet drugs and uses thereof | SHANGHAI CUREGENE PHARMACEUTICAL CO LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| US-20230295089-A1 | ANTIPLATELET DRUGS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-3290423-B1 | OPTICALLY ACTIVE 2-HYDROXY TETRAHYDROTHIENOPYRIDINE DERIVATIVES, PREPARATION METHOD AND USE IN MANUFACTURE OF MEDICAMENT THEREOF | JIANGSU VCARE PHARMATECH CO LTD (CN) | 2021-07-21 | — | — | EP | disclosed |
| CN-112812098-A | Preparation method and medical application of unsaturated cyclic amine pyridine disulfide derivative | 北京沃邦医药科技有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112778371-A | Thienopyridine derivative and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| US-20120053157-A1 | METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM | IPCA LABORATORIES LIMITED (IN) | 2012-03-01 | — | — | US | disclosed |
| US-20120053157-A1 | METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM | IPCA LABORATORIES LIMITED (IN) | 2012-03-01 | — | — | US | disclosed |
| US-7329751-B2 | Process for the preparation of clopidogrel | DIPHARMA S.P.A. (IT) | 2008-02-12 | — | — | US | disclosed |
| EP-1501838-B1 | A PROCESS FOR THE PREPARATION OF CLOPIDOGREL | DIPHARMA FRANCIS SRL (IT) | 2007-04-11 | — | — | EP | disclosed |
| US-20050143414-A1 | Process for the preparation of clopidogrel | DIPHARMA S.P.A. (IT) | 2005-06-30 | — | — | US | disclosed |
| EP-1501838-A1 | A PROCESS FOR THE PREPARATION OF CLOPIDOGREL | Dinamite Dipharma S.p.A. (in abbreviated form Dipharma S.p.A.) (IT) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093276-A1 | A PROCESS FOR THE PREPARATION OF CLOPIDOGREL | DIPHARMA S.P.A. (IT) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053157-A1 | METHODS FOR THE TREATMENT OR PROPHYLAXIS OF THROMBOSIS OR EMBOLISM | F2, PLAT, SELP | KMT2A 4024/4885ALDH1A1 918/4885POLB 1968/4885 |
| US-11834413-B2 | Antiplatelet drugs and uses thereof | PFKP, GP6, PF4 | KMT2A 4857/4885ALDH1A1 734/4885POLB 3179/4885 |
| US-20050143414-A1 | Process for the preparation of clopidogrel | CYP2C19, P2RY13, CYP2C9 | KMT2A 3325/4885ALDH1A1 774/4885POLB 1736/4885 |
| US-20230295089-A1 | ANTIPLATELET DRUGS AND USES THEREOF | PFKP, GP6, PF4 | KMT2A 4857/4885ALDH1A1 734/4885POLB 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.