Dichloroisoproterenol

Dichloroisoproterenol

SCHEMBL613952

CC(C)NCC(O)c1ccc(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.63
ADRB1 P08588 4/20 0.63
TSHR P16473 4/20 0.63
MAPT P10636 3/20 0.63
HIF1A Q16665 3/20 0.63
ADRB3 P13945 2/20 0.63
MTOR P42345 2/20 0.63
KDM4E B2RXH2 2/20 0.63
MAPK1 P28482 2/20 0.63
HSD17B10 Q99714 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
MEN1 O00255 2/20 0.63
CYP1A2 P05177 2/20 0.63
KMT2A Q03164 2/20 0.63
ADRA1A P35348 2/20 0.63
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
CYP3A4 P08684 1/20 0.63
HPGD P15428 1/20 0.63
NFKB1 P19838 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichloroisoproterenol SCHEMBL29139831 1.00 ADRB2 (0.63) ADRB2ADRB1TSHRMAPTHIF1A
SCHEMBL4628378 0.85 ADRB2 (0.49) ADRB2ADRB1TSHRMAPTHIF1A
SCHEMBL11804077 0.83 ADRB2 (0.55) ADRB2ADRB1TSHRMAPTHIF1A
SCHEMBL6921904 0.82 CYP3A4 (0.61) ADRB2ADRB1TSHRMAPTHIF1A
Palmitic Acid SCHEMBL10780498 0.82 MAPT (0.47) ADRB2ADRB1TSHRMAPTHIF1A
Hydrochloric Acid SCHEMBL11812398 0.82 ADRB2 (0.56) ADRB2ADRB1TSHRMAPTHIF1A
Dichloroisoproterenol SCHEMBL28171414 0.81 CYP1A2 (0.48) ADRB2ADRB1TSHRMAPTHIF1A
Hydrochloric Acid SCHEMBL8565017 0.81 KDM4E (0.62) ADRB2ADRB1TSHRMAPTHIF1A
SCHEMBL10792086 0.81 ALDH1A1 (0.47) ADRB2ADRB1TSHRMAPTHIF1A
SCHEMBL7152589 0.79 ADRB2 (0.65) ADRB2ADRB1TSHRHIF1AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
US-9585884-B2 Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 AUSPEX PHARMACEUTICALS, INC. (US) 2017-03-07 US claimed
US-20170002015-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR AUSPEX PHARMACEUTICALS INC (US) 2017-01-05 US claimed
US-9498481-B2 Cyclopropyl modulators of P2Y12 receptor AUSPEX PHARMACEUTICALS, INC. (US) 2016-11-22 US claimed
US-20160193212-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR AUSPEX PHARMACEUTICALS INC (US) 2016-07-07 US claimed
US-9255104-B2 Cyclopropyl modulators of P2Y12 receptor AUSPEX PHARMACEUTICALS, INC. (US) 2016-02-09 US claimed
US-20140286943-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR AUSPEX PHARMACEUTICALS INC (US) 2014-09-25 US claimed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US claimed
US-8575348-B2 Quinolone inhibitors of lipoprotein-associated phospholipase A2 AUSPEX PHARMACEUTICALS, INC (US) 2013-11-05 US claimed
US-20120301458-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR AUSPEX PHARMACEUTICALS, INC. (US) 2012-11-29 US claimed
WO-2000040232-A2 BRETYLIUM COMPOSITIONS AND KITS, AND THEIR USE IN PREVENTING AND TREATING CARDIOVASCULAR CONDITIONS BACANER MARVIN B (US) 2000-07-13 WO claimed
WO-1996025163-A1 TREATMENT OF HERPES SIMPLEX VIRUSES BOARD OF SUPERVISORS OR LOUISIANA STATE UNIVERSITYOF AGRICULTURAL AND MECHANICAL COLLEGE THROUGH ITSMEDICAL CENTER (US) 1996-08-22 WO claimed
WO-1995032981-A1 NOVEL GLYCOSIDE COMPOUNDS AND PRODUCTION AND USE THEREOF HARRIER, INC. (US) 1995-12-07 WO claimed
US-4898729-A Treatment of hypertension, compounds and compositions for antihypertension and diuresis EUROCELTIQUE, S.A. (LU) 1990-02-06 US claimed
EP-0073819-B1 NASAL ADMINISTRATION OF BETA-BLOCKERS AND DOSAGE FORMS THEREFOR The University of Kentucky Research Foundation (US) 1987-05-27 EP claimed
EP-0154009-A1 Use of a thiazide diuretic for the manufacture of a non-diuretic antihypertensive medicament Euro-Celtique S.A. (LU) 1985-09-11 EP claimed
EP-0073819-A4 NASAL ADMINISTRATION OF BETA-BLOCKERS AND DOSAGE FORMS THEREFOR. UNIV KENTUCKY RES FOUND (US) 1984-11-16 EP claimed
US-4428883-A NASAL OINTMENTS OR GELS THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1984-01-31 US claimed
EP-0073819-A1 NASAL ADMINISTRATION OF BETA-BLOCKERS AND DOSAGE FORMS THEREFOR. UNIV KENTUCKY RES FOUND (US) 1983-03-16 EP claimed
WO-1982003009-A1 NASAL ADMINISTRATION OF BETA-BLOCKERS AND DOSAGE FORMS THEREFOR UNIV KENTUCKY RES FOUND (US) 1982-09-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170002015-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR P2RY12, P2RY11, P2RY2 ADRB2 180/4885ADRB1 152/4885TSHR 1128/4885
US-20160193212-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR P2RY12, P2RY11, P2RY2 ADRB2 180/4885ADRB1 152/4885TSHR 1128/4885
US-20120301458-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR P2RY12, P2RY11, P2RY2 ADRB2 142/4885ADRB1 134/4885TSHR 959/4885
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B ADRB2 1422/4885ADRB1 1713/4885TSHR 3285/4885
US-20140286943-A1 CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR P2RY12, P2RY11, P2RY2 ADRB2 180/4885ADRB1 152/4885TSHR 1128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.