Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR1B | P28222 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910645 | 0.81 | SOS1 (0.51) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL22444632 | 0.79 | MRGPRX4 (0.45) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL24215026 | 0.77 | HSD11B1 (0.45) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL3045676 | 0.77 | TDP1 (0.46) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL2295646 | 0.77 | HTR1D (0.43) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL1980396 | 0.77 | ALDH1A1 (0.43) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL7112365 | 0.76 | ADORA2A (0.43) | CA1CA2HTR1DHTR1AHTR1B | |
| SCHEMBL24987677 | 0.76 | CXCR2 (0.42) | EPAS1CA1CA2HTR1DHTR1A | |
| SCHEMBL4056753 | 0.75 | CA1 (0.51) | CA1CA2HTR1DHTR1AHTR1B | |
| SCHEMBL576035 | 0.74 | CA2 (0.50) | CA1CA2HTR1DHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196403-B1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI AVENTIS (FR) | 2005-11-09 | — | — | EP | disclosed |
| US-6908914-B1 | Antipsychotic cyclic N-aralkylamines | SANOFI-SYNTHELABO (FR) | 2005-06-21 | — | — | US | disclosed |
| CN-1156462-C | Antipsychotic cyclic N-aralkyl amines | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-07-07 | — | — | CN | disclosed |
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | disclosed |
| CN-1367783-A | Antipsychotic cyclic N-aralkyl amines | SANOFI SYNTHELABO (FR) | 2002-09-04 | — | — | CN | disclosed |
| EP-1196403-A1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | Sanofi-Aventis (FR) | 2002-04-17 | — | — | EP | disclosed |
| EP-1192122-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001002380-A1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI-SYNTHELABO (FR) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000076953-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2000-12-21 | — | — | WO | disclosed |