Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329883 | 0.84 | ALDH1A1 (0.64) | ALDH1A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL1330190 | 0.84 | RAB9A (0.67) | ALDH1A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL2430973 | 0.82 | HSP90AA1 (0.74) | ALDH1A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL2430971 | 0.82 | HSP90AA1 (0.74) | ALDH1A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL18272620 | 0.80 | MAPK8 (0.63) | ALDH1A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL601333 | 0.79 | HRH3 (0.54) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3603575 | 0.77 | SMO (0.79) | — | |
| SCHEMBL1330690 | 0.77 | SMN1; SMN2 (0.60) | ALDH1A1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL6140027 | 0.76 | HRH3 (0.58) | ALDH1A1KDM4ELMNAKDM1A | |
| SCHEMBL2494848 | 0.76 | HDAC1 (0.56) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737509-B1 | Antimicrobial compositions, methods of use, and methods of treatment of infections | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-08-22 | — | — | US | disclosed |
| US-9737509-B1 | Antimicrobial compositions, methods of use, and methods of treatment of infections | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-08-22 | — | — | US | disclosed |
| WO-2016191412-A1 | ANTIMICROBIAL COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT OF INFECTIONS | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-12-01 | — | — | WO | disclosed |
| US-6852736-B2 | Phenoxypropanolamines, preparation and therapeutic use thereof | SANOFI-SYNTHELABO (FR) | 2005-02-08 | — | — | US | disclosed |
| US-20030105135-A1 | Phenoxypropanolamines, preparation and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105135-A1 | Phenoxypropanolamines, preparation and therapeutic use thereof | CNR1, ADRB3, ADRB1 | ALDH1A1 637/4885RAB9A 3589/4885SMN1; SMN2 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.