SCHEMBL6139923

SCHEMBL6139923

C=CCc1c(Cc2ccc(N)cc2)ccc(N(CC=C)CC=C)c1CC=C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5333330 0.78
Hydrochloric Acid SCHEMBL10885447 0.77
SCHEMBL6140286 0.71 CYP3A4 (0.52) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL9843625 0.71 CYP3A4 (0.46) ALDH1A1CYP3A4TSHRTDP1HTR6
SCHEMBL4649425 0.68 ALDH1A1 (0.42) ALDH1A1CYP3A4TSHRTDP1HTR6
SCHEMBL2221665 0.65 CASP1 (0.34) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL29499603 0.65 CASP1 (0.34) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL716339 0.65 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL11132266 0.65 CYP3A4 (0.43) ALDH1A1CYP3A4TSHRTDP1HTR6
SCHEMBL11301507 0.65 CHKA (0.40) ALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8828548-B2 Interlayer adhesive, waterproof structure and waterproof construction method DYFLEX CORPORATION (JP) 2014-09-09 US disclosed
US-20130115464-A1 INTERLAYER ADHESIVE, WATERPROOF STRUCTURE AND WATERPROOF CONSTRUCTION METHOD DYFLEX CORPORATION (JP) 2013-05-09 US disclosed
EP-2589635-A1 INTERLAMINAR BONDING AGENT AND WATERPROOF STRUCTURE AND WATERPROOFING METHOD Dyflex Corporation (JP) 2013-05-08 EP disclosed
EP-1260548-B1 Plasticizer and urethane curable composition ASAHI GLASS CO LTD (JP) 2005-03-02 EP disclosed
US-20020198312-A1 Plasticizer and urethane curable composition ASAHI GLASS COMPANY, LIMITED (JP) 2002-12-26 US disclosed
EP-1260548-A1 Plasticizer and urethane curable composition ASAHI GLASS COMPANY LTD. (JP) 2002-11-27 EP disclosed