Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140425 | 0.97 | RAB9A (0.55) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6140778 | 0.80 | MAPT (0.64) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL6639527 | 0.80 | NPC1 (0.54) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6139854 | 0.78 | RAB9A (0.49) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7153521 | 0.76 | NPC1 (0.60) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7151949 | 0.75 | NPC1 (0.54) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1678146 | 0.74 | SMN1; SMN2 (0.54) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL5163049 | 0.74 | NAMPT (0.48) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1677992 | 0.74 | MEN1 (0.60) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7150740 | 0.74 | NPC1 (0.57) | RAB9ANPC1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499591-A1 | CARBOXYLIC ACID AMIDES | MERCK PATENT GmbH (DE) | 2005-01-26 | — | — | EP | claimed |
| WO-2003093235-A1 | CARBOXYLIC ACID AMIDES | MERCK PATENT GMBH (DE) | 2003-11-13 | — | — | WO | claimed |