Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141494 | 0.85 | ALDH1A1 (0.57) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6141495 | 0.85 | ALDH1A1 (0.57) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6140425 | 0.81 | RAB9A (0.55) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6139947 | 0.78 | RAB9A (0.54) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5631939 | 0.71 | CYP1A2 (0.40) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5631940 | 0.71 | CYP1A2 (0.40) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7146259 | 0.71 | RAB9A (0.53) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7157785 | 0.71 | NPC1 (0.58) | RAB9ANPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6139855 | 0.71 | HIF1A (0.38) | — | |
| SCHEMBL6139850 | 0.71 | HIF1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499591-A1 | CARBOXYLIC ACID AMIDES | MERCK PATENT GmbH (DE) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093235-A1 | CARBOXYLIC ACID AMIDES | MERCK PATENT GMBH (DE) | 2003-11-13 | — | — | WO | disclosed |